The presence of Helicobacter pylori (H. pylori), a bacterium, has been linked to higher levels of HbA1c, a diabetes biomarker which is used for measuring blood sugar levels in patients with diabetes. For people with higher BMIs (body mass indexes), the association was even higher...
Saturday, March 17, 2012
Barriers To Diabetes Care In NYC Bangladeshi Community
A new research survey conducted by the Center for the Study of Asian American Health at NYU Langone Medical Center shows the Bangladeshi community in New York City experiences numerous barriers to diabetes care because of limited English proficiency and lack of diabetes awareness...
White Rice Raises Risk Of Diabetes Type 2
According to a study published today on bmj.com, consuming to much white rice regularly considerably increases the risk of developing type 2 diabetes...
Potential Link Between H. pylori Bacteria And Adult Type 2 Diabetes
A recent study shows that the presence of H. pylori bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes. This association was stronger in obese individuals with a higher Body Mass Index (BMI)...
Mechanism Discovered In Cells That Leads To Inflammatory Diseases
Cedars-Sinai researchers have unlocked the mystery of how an inflammatory molecule is produced in the body, a discovery they say could lead to advances in the treatment of rheumatoid arthritis, Type 2 diabetes and numerous other chronic diseases that affect tens of millions of people...
Gut Cells Transformed Into Insulin Factories - A New Approach To Treating Type I Diabetes?
A study by Columbia researchers suggests that cells in the patient's intestine could be coaxed into making insulin, circumventing the need for a stem cell transplant. Until now, stem cell transplants have been seen by many researchers as the ideal way to replace cells lost in type I diabetes and to free patients from insulin injections...
Circadian Rhythm May Hold Key For Treatment Of Bipolar Disorder
Scientists have gained insight into why lithium salts are effective at treating bipolar disorder in what could lead to more targeted therapies with fewer side-effects. Bipolar disorder is characterised by alternating states of elevated mood, or mania, and depression. It affects between 1% and 3% of the general population...
Optimal Threshold Identified For HbA1c Test For Prediabetes
The American Diabetes Association recommends hemoglobin A1c (HbA1c) testing as one basis for identifying diabetes and prediabetes...
Gut Cells Turned To Insulin Factories - New Type l Diabetes Treatment
According to a study conducted in mice by researchers at Columbia University Medical Center and published 11 March 2012, in the journal Nature Genetics, cells in the intestine of patients with type 1 diabetes could be lured into generating insulin, eliminating the need for a stem cell transplant...
Monday, March 12, 2012
ACIP expands recommendations for whooping cough vaccine to 65 and older
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Study: Smoking-cessation aids don’t boost chances of quitting
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Study: Anti-infective drug shortages affect clinical care, outcomes
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First medication approved by FDA for patients with endogenous Cushing's syndrome
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Zinc plus antibiotics saves lives of children with pneumonia, study finds
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Study: Blood clots likely for as many as 1 in 100 following joint replacements
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Acellular pertussis vaccinations increase risk of febrile seizures, study finds
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FDA approves 2 pancreatic enzyme products to aid food digestion
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FDA approves therapies for AMD, insomnia
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California regulates OTC cough and cold products to cut abuse by youths
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AACP joins other healthcare professions to improve education collaboration
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FDA approves preservative-free solution for glaucoma, ocular hypertension
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NCPA, NACDS protest TRICARE limitations in Obama budget
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Anti-infective drug shortages affect clinical care, outcomes
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FDA warning: Co-administration of statins and protease inhibitors increases risk of muscle injury
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Community pharmacists key to improving pain management
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FDA approves extended-release tablets for type 2 diabetes
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What’s new on the shelves?
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Study finds association between open-angle glaucoma and ED
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FDA approves extended use of pneumococcal conjugate vaccine as a single dose to adults 50 years and older
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FDA warns of potential diabetes risk, cognitive adverse events with statins
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Statins cost 4 times more in U.S. than in U.K.
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Varicella vaccination program cuts infection rate in infants, report shows
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AAP now recommends HPV vaccine for boys
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FDA grants priority review to GI agent for controlling diarrhea in HIV/AIDS patients
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Likely New Trigger For Epidemic Of Metabolic Syndrome Discovered
UC Davis scientists have uncovered a key suspect in the destructive inflammation that underlies heart disease and diabetes. The new research shows elevated levels of a receptor present on leucocytes of the innate immune response in people at risk for these chronic diseases...
Improving Glucose Control Without Raising Hypoglycemia Risk, New Drug Shows Promise
Results of a Phase II randomized trial published Online First in The Lancet, reveal that a new treatment for type 2 diabetes called TAK-875, enhances glycemic (blood sugar) control and is just as effective as the common drug treatment - sulphonylurea glimepiride. In addition, TAK-875 has less adverse effects and a considerably lower risk of hypoglycemia (low blood sugar)...
Selenium Supplements May Harm Not Help
According to a recent study, published Online First in The Lancet , selenium may help people who don't have enough of it, but for the people who have enough to begin with, selenium supplements may be detrimental to their health. It is shown in the study that taking the supplements may result in the development of type 2 diabetes...
How Added Sugar In Diet Leads To Obesity, Diabetes - New Clues About Fructose
A new animal study published on Monday in the Proceedings of the National Academy of Sciences, offers new clues about the mechanism through which a diet high in fructose, such as from added sugar and high fructose corn syrup, may contribute to the development of obesity and diabetes...
Atherosclerosis Progression Halted By Metformin In HIV-Infected Patients
Treatment with the common diabetes drug metformin appears to prevent progression of coronary atherosclerosis in patients infected with HIV...
Key Molecule Targeted To Reverse Kidney Damage In Mice
In findings that may lead to clinical trials of a promising new drug for kidney disease, researchers at Beth Israel Deaconess Medical Center (BIDMC) and their colleagues have identified a key molecular player and shown how a targeted experimental drug can reverse kidney damage in mouse models of diabetes, high blood pressure, genetic kidney disease, and other kidney injuries...
'The Roadmap To Close The Gap For Vision' - $70 Million Could Save The Sight Of Indigenous Australians
Presently Indigenous Australians suffer six times the blindness of mainstream Australians and 94 percent of vision loss in Indigenous Australians is unnecessary, preventable or treatable. 'The Roadmap to Close the Gap for Vision' is the first comprehensive framework to 'close the gap' on Indigenous eye health and draws together more than five years extensive research and consultation...
TAK-875 - New Treatment For Type 2 Diabetes
The Lancet published results of a phase 2, randomized trial of TAK-875, a new treatment for type 2 diabetes online, which demonstrates that it is comparative to glimepiride in its ability to improve blood sugar control, but the risk of hypoglycemia, i.e. creating dangerous drops in blood sugar levels is substantially lower. Of the 150 million diabetics currently living in the U.S...
Insight Into How Fructose Causes Obesity And Other Illness
A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes. In this study which was performed in lab animals, researchers found that fructose can be metabolized by an enzyme that exists in two forms...
A TRP That Makes Our Cells Feel Hyper
A large change in the volume of a cell, from its basal level, is detrimental to its health. Therefore, our cells are equipped with mechanisms to maintain their constant volume. When a cell detects an environmental change that will alter its volume, due to changes in the osmotic pressure, it will adjust its internal water content to counter these influences...
Glycemic Control Improved In Vivo By Allosteric Insulin Receptor-Activating Antibody
XOMA Corporation (Nasdaq: XOMA) announced that its study of XMetA, the company's fully-human allosteric monoclonal antibody to the insulin receptor, is available online and will be published in the May issue of the American Diabetes Association's journal Diabetes. XMetA is the first antibody specific for the insulin receptor shown to correct hyperglycemia in a mouse model of diabetes...
Public Health Data Reveals Obesity, Hypertension, And Diabetes Prevalence In Cleveland Neighborhoods
The Prevention Research Center for Healthy Neighborhoods of Case Western Reserve University has released new health data from Cleveland neighborhood groups on three of the most pressing public health concerns: obesity, hypertension, and diabetes...
Revolutionary Oxygen-Generating Biomaterial To Enhance Islet Survival Developed By Diabetes Research Institute
Scientists at the Diabetes Research Institute have developed a revolutionary technique to provide critical oxygen for maintaining the survival of insulin-producing cells. This is the first time that scientists have been able to successfully deliver oxygen locally to beta cells using a biomaterial...
Why The Immune System Specifically Attacks Beta Cells In Type 1 Diabetes
A new JDRF-funded study shows that many of the genes known to play a role in type 1 diabetes (T1D) are expressed in pancreatic beta cells, suggesting that the cell responsible for producing insulin may be playing a part in its own destruction to lead to T1D...
Causes Of Mortality In Older People In Latin America, India And China
Stroke is the leading cause of death in people over 65 in low- and middle-income countries, according to new research published this week. Deaths of people over 65 represent more than a third of all deaths in developing countries yet, until now, little research has focused on this group. The study was led by researchers King's College London and is published in PLoS Medicine...
TAK-875 For Treatment Of Type 2 Diabetes
A study published Online First in The Lancet , states that TAK-875, a new medicine used for treating type 2 diabetes, is a safe way to improve the control of blood sugar and is said to have minimal risk of low blood sugar. However, there are some side effects...
Wound Healing Promoted In Vivo By Novel Bioactive Peptides
Researchers have combined bioactive peptides to successfully stimulate wound healing. The in vitro and in vivo study, published today in PLoS ONE, demonstrates that the combination of two peptides stimulates the growth of blood vessels and promotes re-growth of tissue. Further development of these peptides could lead to a new treatment for chronic and acute wounds...
Survival And Susceptibility To Common Diseases Impacted By Circadian Nitrogen Balance
Researchers at Case Western Reserve University School of Medicine demonstrated that nitrogen balance, the process of utilizing amino acids and disposing of their toxic byproducts, occurs with a precise 24-hour rhythm - also known as circadian rhythm - in mammals...
Skeletal Muscle Function May Be Enhanced By Epicatechin-Enriched Cocoa
A small clinical trial led by researchers at UC San Diego School of Medicine and VA San Diego Healthcare System (VASDHS) found that patients with advanced heart failure and type 2 diabetes showed improved mitochondrial structure after three months of treatment with epicatechin-enriched cocoa. Epicatechin is a flavonoid found in dark chocolate...
Long-time Diabetics Have Increased Risk Of Stroke
The longer you have diabetes, the higher your risk for stroke, according to a study in Stroke, an American Heart Association journal. In the study, diabetes increased stroke risk 3 percent each year and tripled the risk for people who had diabetes for 10 years or more, compared to people without diabetes...
Overweight People May Benefit From Active Breaks During Prolonged Sitting
Interrupting prolonged periods of sitting with regular, two-minute breaks of light or moderate intensity activity like walking may be good for overweight and obese people's health, because new research reported recently in Diabetes Care shows it helped their bodies keep glucose and insulin levels under control after consuming the equivalent of a high calorie meal ("po...
A Step Closer To Understanding Autoimmune Diseases
Understanding why immune cells, called T-cells, attack the body is vital in the war against autoimmune diseases like diabetes. University of Alberta researcher Troy Baldwin is a step closer to understanding why the body's T-cells sometimes attack healthy cells causing autoimmune diseases...
New Study Shows High Insulin Resistance Is Correlated With Rapid Decline In Renal Function In Elderly Populations
Elderly people with the metabolic syndrome - defined as having multiple risk factors associated with developing diabetes and heart disease - had an increased risk of chronic kidney disease, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM)...
New Diabetes Drug Improves Glucose Control Without Increasing Risk Of Hypoglycemia
TAK-875, a new treatment for type 2 diabetes, improves blood sugar control and is equally effective as glimepiride, but has a significantly lower risk of creating a dangerous drop in blood sugar, called hypoglycemia, according to a new study. The results of the phase 2 randomized trial were published Online First in The Lancet...
Enabling Women To Spend Less Time Sitting Could Reduce Diabetes Risk
A new study has found that women who stay seated for long periods of time every day are more prone to developing type 2 diabetes, but that a similar link wasn't found in men...
Saturday, March 10, 2012
Key Molecule Targeted To Reverse Kidney Damage In Mice
In findings that may lead to clinical trials of a promising new drug for kidney disease, researchers at Beth Israel Deaconess Medical Center (BIDMC) and their colleagues have identified a key molecular player and shown how a targeted experimental drug can reverse kidney damage in mouse models of diabetes, high blood pressure, genetic kidney disease, and other kidney injuries...
Atherosclerosis Progression Halted By Metformin In HIV-Infected Patients
Treatment with the common diabetes drug metformin appears to prevent progression of coronary atherosclerosis in patients infected with HIV...
TAK-875 - New Treatment For Type 2 Diabetes
The Lancet published results of a phase 2, randomized trial of TAK-875, a new treatment for type 2 diabetes online, which demonstrates that it is comparative to glimepiride in its ability to improve blood sugar control, but the risk of hypoglycemia, i.e. creating dangerous drops in blood sugar levels is substantially lower. Of the 150 million diabetics currently living in the U.S...
'The Roadmap To Close The Gap For Vision' - $70 Million Could Save The Sight Of Indigenous Australians
Presently Indigenous Australians suffer six times the blindness of mainstream Australians and 94 percent of vision loss in Indigenous Australians is unnecessary, preventable or treatable. 'The Roadmap to Close the Gap for Vision' is the first comprehensive framework to 'close the gap' on Indigenous eye health and draws together more than five years extensive research and consultation...
Selenium Supplements May Harm Not Help
According to a recent study, published Online First in The Lancet , selenium may help people who don't have enough of it, but for the people who have enough to begin with, selenium supplements may be detrimental to their health. It is shown in the study that taking the supplements may result in the development of type 2 diabetes...
Tackling Diabetes Care Challenges - Expert Groups Collaborate
The Endocrine Society, the American Pharmacists Association (APhA) and Opus Science, announce the launch of their new program in an effort to assess and improve care for those suffering from diabetes. The program called "Improving Quality in Type 2 Diabetes: A National Initiative to Assess Guideline Adherence and Physician/Pharmacist Coordination," is part of a new U.S...
Insight Into How Fructose Causes Obesity And Other Illness
A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes. In this study which was performed in lab animals, researchers found that fructose can be metabolized by an enzyme that exists in two forms...
Overweight People May Benefit From Active Breaks During Prolonged Sitting
Interrupting prolonged periods of sitting with regular, two-minute breaks of light or moderate intensity activity like walking may be good for overweight and obese people's health, because new research reported recently in Diabetes Care shows it helped their bodies keep glucose and insulin levels under control after consuming the equivalent of a high calorie meal ("po...
Revolutionary Oxygen-Generating Biomaterial To Enhance Islet Survival Developed By Diabetes Research Institute
Scientists at the Diabetes Research Institute have developed a revolutionary technique to provide critical oxygen for maintaining the survival of insulin-producing cells. This is the first time that scientists have been able to successfully deliver oxygen locally to beta cells using a biomaterial...
Enabling Women To Spend Less Time Sitting Could Reduce Diabetes Risk
A new study has found that women who stay seated for long periods of time every day are more prone to developing type 2 diabetes, but that a similar link wasn't found in men...
Revising The 'Textbook' On Liver Metabolism Offers New Targets For Diabetes Drugs
A team led by researchers from the Institute for Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine, University of Pennsylvania, has overturned a "textbook" view of what the body does after a meal. The study appears online this week in Nature Medicine, in advance of print publication...
Skeletal Muscle Function May Be Enhanced By Epicatechin-Enriched Cocoa
A small clinical trial led by researchers at UC San Diego School of Medicine and VA San Diego Healthcare System (VASDHS) found that patients with advanced heart failure and type 2 diabetes showed improved mitochondrial structure after three months of treatment with epicatechin-enriched cocoa. Epicatechin is a flavonoid found in dark chocolate...
TAK-875 For Treatment Of Type 2 Diabetes
A study published Online First in The Lancet , states that TAK-875, a new medicine used for treating type 2 diabetes, is a safe way to improve the control of blood sugar and is said to have minimal risk of low blood sugar. However, there are some side effects...
New Study Shows High Insulin Resistance Is Correlated With Rapid Decline In Renal Function In Elderly Populations
Elderly people with the metabolic syndrome - defined as having multiple risk factors associated with developing diabetes and heart disease - had an increased risk of chronic kidney disease, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM)...
Long-time Diabetics Have Increased Risk Of Stroke
The longer you have diabetes, the higher your risk for stroke, according to a study in Stroke, an American Heart Association journal. In the study, diabetes increased stroke risk 3 percent each year and tripled the risk for people who had diabetes for 10 years or more, compared to people without diabetes...
Diabetic Polyneuropathies May Not Be Explained By Prediabetes
In a reversal of two decades of medical reports, a Mayo Clinic study finds the frequency of nerve damage called diabetic polyneuropathy is similar in prediabetic patients and healthy people. Physicians should seek explanations other than prediabetes for patients who have painful small fiber polyneuropathy, the researchers say. The study was published in the March issue of Diabetes Care...
Wound Healing Promoted In Vivo By Novel Bioactive Peptides
Researchers have combined bioactive peptides to successfully stimulate wound healing. The in vitro and in vivo study, published today in PLoS ONE, demonstrates that the combination of two peptides stimulates the growth of blood vessels and promotes re-growth of tissue. Further development of these peptides could lead to a new treatment for chronic and acute wounds...
Improving Glucose Control Without Raising Hypoglycemia Risk, New Drug Shows Promise
Results of a Phase II randomized trial published Online First in The Lancet, reveal that a new treatment for type 2 diabetes called TAK-875, enhances glycemic (blood sugar) control and is just as effective as the common drug treatment - sulphonylurea glimepiride. In addition, TAK-875 has less adverse effects and a considerably lower risk of hypoglycemia (low blood sugar)...
How Added Sugar In Diet Leads To Obesity, Diabetes - New Clues About Fructose
A new animal study published on Monday in the Proceedings of the National Academy of Sciences, offers new clues about the mechanism through which a diet high in fructose, such as from added sugar and high fructose corn syrup, may contribute to the development of obesity and diabetes...
Public Health Data Reveals Obesity, Hypertension, And Diabetes Prevalence In Cleveland Neighborhoods
The Prevention Research Center for Healthy Neighborhoods of Case Western Reserve University has released new health data from Cleveland neighborhood groups on three of the most pressing public health concerns: obesity, hypertension, and diabetes...
Survival And Susceptibility To Common Diseases Impacted By Circadian Nitrogen Balance
Researchers at Case Western Reserve University School of Medicine demonstrated that nitrogen balance, the process of utilizing amino acids and disposing of their toxic byproducts, occurs with a precise 24-hour rhythm - also known as circadian rhythm - in mammals...
A Step Closer To Understanding Autoimmune Diseases
Understanding why immune cells, called T-cells, attack the body is vital in the war against autoimmune diseases like diabetes. University of Alberta researcher Troy Baldwin is a step closer to understanding why the body's T-cells sometimes attack healthy cells causing autoimmune diseases...
Causes Of Mortality In Older People In Latin America, India And China
Stroke is the leading cause of death in people over 65 in low- and middle-income countries, according to new research published this week. Deaths of people over 65 represent more than a third of all deaths in developing countries yet, until now, little research has focused on this group. The study was led by researchers King's College London and is published in PLoS Medicine...
New Diabetes Drug Improves Glucose Control Without Increasing Risk Of Hypoglycemia
TAK-875, a new treatment for type 2 diabetes, improves blood sugar control and is equally effective as glimepiride, but has a significantly lower risk of creating a dangerous drop in blood sugar, called hypoglycemia, according to a new study. The results of the phase 2 randomized trial were published Online First in The Lancet...
Likely New Trigger For Epidemic Of Metabolic Syndrome Discovered
UC Davis scientists have uncovered a key suspect in the destructive inflammation that underlies heart disease and diabetes. The new research shows elevated levels of a receptor present on leucocytes of the innate immune response in people at risk for these chronic diseases...
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